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Vorasidenib gains approval from NICE

31 March 2026 31 March 2026 | Blog, Campaigning and research, News, Treatments

The NICE logo with image of container of the drug Vorasidenib and molecular diagram on a teal background
At Brain Tumour Support, we have been closely following developments around Vorasidenib, a targeted therapy that has shown promise for people living with certain types of low-grade glioma. So we are delighted to share today’s final decision by the National Institute for Health and Care Excellence (NICE) to approve Vorasidenib for use on the NHS in England.

The final draft guidance released today by NICE follows the drug’s earlier approval in Scotland, and means that more people across the UK living with certain types of low-grade glioma may now be able to access this treatment.

What is Vorasidenib?

Vorasidenib is a targeted therapy in tablet form. It works by inhibiting mutated IDH1 and IDH2 enzymes, which can drive tumour growth in some low-grade gliomas such as astrocytoma and oligodendroglioma.

Clinical trial evidence has shown that the drug can delay tumour progression and may help postpone the need for treatments such as radiotherapy and chemotherapy for some patients.  The decision from NICE gives access to Vorasidenib for people aged 12 or older and will depend on certain criteria and be determined by a patient’s clinical team. If you think this treatment may be relevant to you or a loved one, we encourage you to speak with them. Access may take a little time to become fully established across all centres, but your team will be able to advise on availability.

How we can support you

We understand that news like this can bring both hope and also raise questions. Our team is here to support you, if you would like to speak to someone, please get in touch with your Support Professional, contact our support line on 01454 422 701, or email support@braintumoursupport.co.uk.

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